bnn, Author at DeDNAed

DeDNAed featured in Spanish Perspectivas AseBio

The DeDNAed biosensor platform will be used to detect biomolecules, enabling the detection of food toxins or disease biomarkers.

Ultra-sensitive biosensor using DNA origami developed by 7 European partners

The DeDNAed biosensor platform will be used to detect biomolecules, enabling the detection of food toxins or disease biomarkers.

KSI produces DNA origami structures and hybrid structures

KSI Meinsberg, partner in DeDNAed, makes DNA origami and DNA origami hybrid structures for partners’ labs to measure.

UP includes biorecognition elements and analyte pairs in DeDNAed biosensor

In addition to coordinating the DeDNAed project, TU Chemnitz leads the “Integration of DNA origami hybrids” and “Transfer to flexible substrates and biosafety”. They are a bridge between the nanocomponents.

DeDNAed @ European South Atlantic Biophysics Congress

The European South Atlantic Biophysics Congress 2024 took place in Donostia – San Sebastian, Spain, from 5-7 June 2024.

Two DeDNAed partners attended. Mathis Janßen of TU Chemnitz presented a poster “Determination of Mg-Ion concentration in DNA Origami in buffer solutions“.

Aitziber López Cortajarena, PhD. (CIC biomaGUNE) gave an overview during the satellite event.

View the program here.

DeDNAed Final Webinar Recording

On 17 July 2024, the DeDNAed partners gathered online for our final dissemination webinar, entitled “Uniting disciplines: How DeDNAed combines physics and biology for novel biosensor development”.

Coordinator Danny Reuter (Technical University of Chemnitz) welcomed the participants and provided an overview of the DeDNAed project, its goals and consortium. Then Andreas Heerwig of the Kurt-Schwabe-Institut für Mess- und Sensortechnik Meinsberg e.V. (KSI Meinsberg), explained “DNA origami as a tool for precise positioning of sensing elements towards quantitative SERS measurements”.

This was followed by our CIC biomaGUNE partner Itziar Galarreta-Rodriguez, who spoke about “ssDNA aptamers as biorecognition elements for DNA origami biosensor application”. Staying in San Sebastian, we then jumped to partner TECNALIA: Verónica Mora Sanz explained “Antibody-protected bimetallic nanoclusters as biorecognition and transduction element in a DNA-origami based biosensor”.

The first section closed with Saloni Agarwal of University of Potsdam, speaking about “Characterising binding affinity of bio-recognition elements and their targets using switchSENSE technology.”

After a short break, we returned to Julia Voglhuber-Höller of BioNanoNet Forschungsgesellschaft mbH (BNN), who outlined “How Safe(-and-Sustainable)-by-Design can support innovations in the biosensor field”. She was followed by DeDNAed project manager Julia Hann, also of TU Chemnitz, who spoke about “Spatially resolved integration of heterogeneous DNA origami nanosystems on nanostructured surfaces for SERS”.

Finally, Aicha Azziz of the University of Le Mans explained “SERS detection of benzophenone using DNA origami hybrids”. The webinar was moderated by Caitlin Ahern of BNN.

The webinar attracted 50 live participants and ended with a Q&A session.

The recording can be viewed below!

View Agenda

Safe-by-Design Poster at Nanotexnology

Julia Voglhuber-Höller presented a poster on Safe-by-Design in DeDNAed at the Nanotexnology 2024 conference in Thessaloniki, Greece from June 3-5th.

Uniting disciplines: How DeDNAed combines physics and biology for novel biosensor development

As the H2020 project DeDNAed comes to an end in August 2024, we are proud to share some achievements of this ambitious project, creating cluster-decorated recognition elements on DNA origami for enhanced Raman spectroscopic detection methods.

You will hear from experts on wafer processing and surface immobilization, Bio-RE characterization, funcationalization of nanoparticles, antibody clusters, Safe-by-Design and more.