The European South Atlantic Biophysics Congress 2024 took place in Donostia – San Sebastian, Spain, from 5-7 June 2024.
Two DeDNAed partners attended. Mathis JanÃen of TU Chemnitz presented a poster “Determination of Mg-Ion concentration in DNA Origami in buffer solutions“.Â
Aitziber LÃģpez Cortajarena, PhD. (CIC biomaGUNE) gave an overview during the satellite event.
View the program here.
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On 17 July 2024, the DeDNAed partners gathered online for our final dissemination webinar, entitled “Uniting disciplines: How DeDNAed combines physics and biology for novel biosensor development”.
Coordinator Danny Reuter (Technical University of Chemnitz) welcomed the participants and provided an overview of the DeDNAed project, its goals and consortium. Then Andreas Heerwig of the Kurt-Schwabe-Institut fÞr Mess- und Sensortechnik Meinsberg e.V. (KSI Meinsberg), explained “DNA origami as a tool for precise positioning of sensing elements towards quantitative SERS measurements”.
This was followed by our CIC biomaGUNE partner Itziar Galarreta-Rodriguez, who spoke about “ssDNA aptamers as biorecognition elements for DNA origami biosensor application”. Staying in San Sebastian, we then jumped to partner TECNALIA: VerÃģnica Mora Sanz explained “Antibody-protected bimetallic nanoclusters as biorecognition and transduction element in a DNA-origami based biosensor”.
The first section closed with Saloni Agarwal of University of Potsdam, speaking about “Characterising binding affinity of bio-recognition elements and their targets using switchSENSE technology.”
After a short break, we returned to Julia Voglhuber-HÃķller of BioNanoNet Forschungsgesellschaft mbH (BNN), who outlined “How Safe(-and-Sustainable)-by-Design can support innovations in the biosensor field”. She was followed by DeDNAed project manager Julia Hann, also of TU Chemnitz, who spoke about “Spatially resolved integration of heterogeneous DNA origami nanosystems on nanostructured surfaces for SERS”.
Finally, Aicha Azziz of the University of Le Mans explained “SERS detection of benzophenone using DNA origami hybrids”. The webinar was moderated by Caitlin Ahern of BNN.
The webinar attracted 50 live participants and ended with a Q&A session.
The recording can be viewed below!
Julia Voglhuber-HÃķller presented a poster on Safe-by-Design in DeDNAed at the Nanotexnology 2024 conference in Thessaloniki, Greece from June 3-5th.
As the H2020 project DeDNAed comes to an end in August 2024, we are proud to share some achievements of this ambitious project, creating cluster-decorated recognition elements on DNA origami for enhanced Raman spectroscopic detection methods.Â
You will hear from experts on wafer processing and surface immobilization, Bio-RE characterization, funcationalization of nanoparticles, antibody clusters, Safe-by-Design and more.Â
Register now to join us!
DeDNAed was featured in the latest BNN QUARTERLY issue (June 2024).
Watch this video for a step-by-step demonstration of immobilizing DNA origami (hybrids) on Parylen surfaces, from the DeDNAed partners.
In addition to coordinating the DeDNAed project, TU Chemnitz leads the âIntegration of DNA origami hybridsâ and âTransfer to flexible substrates and biosafetyâ. They are a bridge between the nanocomponents.
DeDNAed partner BNN generates a Safe-by-Design (SbD) concept for the sensor platform. In addition, BNN manages the communication and dissemination activities for the H2020 project.
DeDNAed partner TECNALIA is working with antibodies decorated with nanoclusters as well as nanobodies. They also lead the exploitation of the project.
The Institute of Molecules and Materials of Le Mans (IMMM) is in charge of the characterization of the optical and plasmonic properties of the nanostructures included in the bioanalytical platform. It also determines the SERS efficiency and the sensing performances of the platform. Finally, it is involved in the validation of the sensor for food and biomedical applications.
