The European South Atlantic Biophysics Congress 2024 took place in Donostia – San Sebastian, Spain, from 5-7 June 2024.

Two DeDNAed partners attended. Mathis Janßen of TU Chemnitz presented a poster “Determination of Mg-Ion concentration in DNA Origami in buffer solutions“. 

Aitziber López Cortajarena, PhD. (CIC biomaGUNE) gave an overview during the satellite event.

View the program here.

On 17 July 2024, the DeDNAed partners gathered online for our final dissemination webinar, entitled “Uniting disciplines: How DeDNAed combines physics and biology for novel biosensor development”.

Coordinator Danny Reuter (Technical University of Chemnitz) welcomed the participants and provided an overview of the DeDNAed project, its goals and consortium. Then Andreas Heerwig of the Kurt-Schwabe-Institut für Mess- und Sensortechnik Meinsberg e.V. (KSI Meinsberg), explained “DNA origami as a tool for precise positioning of sensing elements towards quantitative SERS measurements”.

This was followed by our CIC biomaGUNE partner Itziar Galarreta-Rodriguez, who spoke about “ssDNA aptamers as biorecognition elements for DNA origami biosensor application”. Staying in San Sebastian, we then jumped to partner TECNALIA: Verónica Mora Sanz explained “Antibody-protected bimetallic nanoclusters as biorecognition and transduction element in a DNA-origami based biosensor”.

The first section closed with Saloni Agarwal of University of Potsdam, speaking about “Characterising binding affinity of bio-recognition elements and their targets using switchSENSE technology.”

After a short break, we returned to Julia Voglhuber-Höller of BioNanoNet Forschungsgesellschaft mbH (BNN), who outlined “How Safe(-and-Sustainable)-by-Design can support innovations in the biosensor field”. She was followed by DeDNAed project manager Julia Hann, also of TU Chemnitz, who spoke about “Spatially resolved integration of heterogeneous DNA origami nanosystems on nanostructured surfaces for SERS”.

Finally, Aicha Azziz of the University of Le Mans explained “SERS detection of benzophenone using DNA origami hybrids”. The webinar was moderated by Caitlin Ahern of BNN.

The webinar attracted 50 live participants and ended with a Q&A session.

The recording can be viewed below!

As the H2020 project DeDNAed comes to an end in August 2024, we are proud to share some achievements of this ambitious project, creating cluster-decorated recognition elements on DNA origami for enhanced Raman spectroscopic detection methods. 

You will hear from experts on wafer processing and surface immobilization, Bio-RE characterization, funcationalization of nanoparticles, antibody clusters, Safe-by-Design and more. 

Register now to join us!

The MAIN research center at the Technical University of Chemnitz (TUC) hosted its MAIN Focus Day on Quantum Dots on 18 January 2024.

The event consisted of 2 research seminars held at the MAIN facilities and a colloquium in the central auditorium.

Julia Hann presented a poster showing the possibility of integrating quantum dots with the DNA origami on surfaces, using the example of our activities in nanoparticles and biomolecules with DeDNAed.

More information about the event (in German) can be found here.

From November 8-10, 2023, the DeDNAed consortium gathered for our M30 General Assembly, hosted by our partner the University of Potsdam.

The program started with work package presentations and discussion of the project’s progress, challenges and achievements. Members of our Advisory Board were present to provide valuable feedback, as well.

All partners then joined for hands-on experiments, delving deep into methodologies crucial for the development of our biosensing platform.

View some impressions from our General Assembly and group experiment here!